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ZUFSP Antibody (N-term) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession Q96AP4
Other Accession NP_659499.2
Clone Names 91208144
Peptide ID 91208144
Additional Information
Gene ID 221302
Other Names Zinc finger with UFM1-specific peptidase domain protein, ZUFSP, C6orf113
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name ZUFSP
Synonyms C6orf113
Function Deubiquitinase with endodeubiquitinase activity that specifically interacts with and cleaves 'Lys-63'-linked long polyubiquitin chains. Shows only weak activity against 'Lys-11' and 'Lys-48'-linked chains (PubMed:29576528, PubMed:29563501, PubMed:29476094). Plays an important role in genome stability pathways, functioning to prevent spontaneous DNA damage and also promote cellular survival in response to exogenous DNA damage (PubMed:29576528, PubMed:29576527). Modulates the ubiquitination status of replication protein A (RPA) complex proteins in response to replication stress (PubMed:29563501).
Cellular Location Cytoplasm. Nucleus. Note=Mostly present in the nuclear fraction. Localizes to DNA lesions.
Research Areas
Citations (0)

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References

Mungall, A.J., et al. Nature 425(6960):805-811(2003)

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$ 80.00
Cat# BP10653a
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