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CES2 Antibody (Center) Blocking peptide

Synthetic peptide

Product Information
Primary Accession O00748
Clone Names 80410116
Peptide ID 80410116
Additional Information
Gene ID 8824
Other Names Cocaine esterase, Carboxylesterase 2, CE-2, hCE-2, Methylumbelliferyl-acetate deacetylase 2, CES2, ICE
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name CES2
Synonyms ICE
Function Involved in the detoxification of xenobiotics and in the activation of ester and amide prodrugs. Shows high catalytic efficiency for hydrolysis of cocaine, 4-methylumbelliferyl acetate, heroin and 6-monoacetylmorphine.
Cellular Location Endoplasmic reticulum lumen.
Tissue Location Preferentially expressed in intestine with moderate expression in liver. Within the intestine, highest expression is found in small intestine with lower expression in colon and rectum.
Research Areas
Citations (0)

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CES2 is a member of the carboxylesterase largefamily. The family members are responsible for the hydrolysis ortransesterification of various xenobiotics, such as cocaine andheroin, and endogenous substrates with ester, thioester, or amidebonds. They may participate in fatty acyl and cholesterol estermetabolism, and may play a role in the blood-brain barrier system.The protein encoded by this gene is the major intestinal enzyme andfunctions in intestine drug clearance.


Holmes, R.S., et al. Mamm. Genome 21 (9-10), 427-441 (2010) :Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)Howard, T.D., et al. Environ. Health Perspect. 118(10):1395-1399(2010)Hatfield, M.J., et al. Br. J. Pharmacol. 160(8):1916-1928(2010)Holmes, R.S., et al. Genetica 138(7):695-708(2010)

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$ 80.00
Cat# BP10661c
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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