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NPSR1 Antibody (C-term) Blocking peptide

Synthetic peptide

Product Information
Primary Accession Q6W5P4
Clone Names 90713154
Peptide ID 90713154
Additional Information
Gene ID 387129
Other Names Neuropeptide S receptor, G-protein coupled receptor 154, G-protein coupled receptor PGR14, G-protein coupled receptor for asthma susceptibility, NPSR1, GPR154, GPRA, PGR14
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name NPSR1
Synonyms GPR154, GPRA, PGR14
Function G-protein coupled receptor for neuropeptide S (NPS) (PubMed:16790440). Promotes mobilization of intracellular Ca(2+) stores (PubMed:16790440). Inhibits cell growth in response to NPS binding (PubMed:15947423). Involved in pathogenesis of asthma and other IgE-mediated diseases.
Cellular Location Isoform 1: Cell membrane; Multi- pass membrane protein Isoform 4: Cell membrane; Multi-pass membrane protein Isoform 5: Cytoplasm Isoform 7: Cytoplasm
Tissue Location Isoform 4 is ubiquitous; it is detected in glandular epithelia of bronchus, stomach, small intestine, colon, uterus, esophagus, spleen, kidney, pancreas, prostate and breast Isoform 1 is detected in uterus, colon and prostate, and in the smooth muscle cell layer in bronchial and arterial walls (at protein level) (PubMed:15947423). Isoform 1 is predominantly expressed in smooth muscle. Isoform 4 is predominantly expressed in epithelial cells. In bronchial biopsies, it is expressed in smooth muscle cells of asthma patients, but not in control patients; whereas in epithelial cells, its expression is consistently stronger in asthma patients
Research Areas
Citations (0)

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NPSR1 is a member of the G protein-coupled receptor 1family and encodes a plasma membrane protein. Increased expressionof this gene in ciliated cells of the respiratory epithelium and inbronchial smooth muscle cells is associated with asthma.


Raczka, K.A., et al. Mol. Psychiatry 15 (11), 1045 (2010) :Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)Donner, J., et al. Biol. Psychiatry 68(5):474-483(2010)Domschke, K., et al. Mol. Psychiatry (2010) In press :Schuurhof, A., et al. Pediatr. Pulmonol. 45(6):608-613(2010)

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$ 80.00
Cat# BP10683b
Availability: In Stock
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