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IL12_2 Antibody (C-term) Blocking peptide

Synthetic peptide

Product Information
Primary Accession Q99665
Clone Names 90723062
Peptide ID 90723062
Additional Information
Gene ID 3595
Other Names Interleukin-12 receptor subunit beta-2, IL-12 receptor subunit beta-2, IL-12R subunit beta-2, IL-12R-beta-2, IL-12RB2, IL12RB2
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name IL12RB2
Function Receptor for interleukin-12. This subunit is the signaling component coupling to the JAK2/STAT4 pathway. Promotes the proliferation of T-cells as well as NK cells. Induces the promotion of T-cells towards the Th1 phenotype by strongly enhancing IFN-gamma production.
Cellular Location Membrane; Single-pass type I membrane protein
Tissue Location Isoform 2 is expressed at similar levels in both naive and activated T-cells.
Research Areas
Citations (0)

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The protein encoded by this gene is a type I transmembraneprotein identified as a subunit of the interleukin 12 receptorcomplex. The coexpression of this and IL12RB1 proteins was shown tolead to the formation of high-affinity IL12 binding sites andreconstitution of IL12 dependent signaling. The expression of thisgene is up-regulated by interferon gamma in Th1 cells, and plays arole in Th1 cell differentiation. The up-regulation of this gene isfound to be associated with a number of infectious diseases, suchas Crohn's disease and leprosy, which is thought to contribute tothe inflammatory response and host defense.


Romero, R., et al. Am. J. Obstet. Gynecol. 203 (4), 361 (2010) :Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)Liu, X., et al. Nat. Genet. 42(8):658-660(2010)Mizuki, N., et al. Nat. Genet. 42(8):703-706(2010)Remmers, E.F., et al. Nat. Genet. 42(8):698-702(2010)

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$ 80.00
Cat# BP10687b
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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