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COL18A1 Antibody (Center) Blocking peptide

Synthetic peptide

Product Information
Primary Accession P39060
Clone Names 90904121
Peptide ID 90904121
Additional Information
Gene ID 80781
Other Names Collagen alpha-1(XVIII) chain, Endostatin, COL18A1
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name COL18A1
Function COLA18A probably plays a major role in determining the retinal structure as well as in the closure of the neural tube.
Cellular Location Secreted, extracellular space, extracellular matrix
Tissue Location Present in multiple organs with highest levels in liver, lung and kidney
Research Areas
Citations (0)

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COL18A1 is the alpha chain of type XVIII collagen.This collagen is one of the multiplexins, extracellular matrixproteins that contain multiple triple-helix domains (collagenousdomains) interrupted by non-collagenous domains. Theproteolytically produced C-terminal fragment of type XVIII collagenis endostatin, a potent antiangiogenic protein. Mutations in thisgene are associated with Knobloch syndrome. The main features ofthis syndrome involve retinal abnormalities, so type XVIII collagenmay play an important role in retinal structure and in neural tubeclosure.


Hamano, Y., et al. J. Am. Soc. Nephrol. 21(9):1445-1455(2010)Roberts, K.E., et al. Gastroenterology 139(1):130-139(2010)Lee, K.S., et al. Tumour Biol. 31(3):165-170(2010)Faye, C., et al. Biochem. J. 427(3):467-475(2010)Polikarpova, S.B., et al. Bull. Exp. Biol. Med. 148(4):634-637(2009)

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$ 80.00
Cat# BP10706c
(40 western blots)
Availability: In Stock
Bulk Size
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