|Other Names||Ectonucleoside triphosphate diphosphohydrolase 3, NTPDase 3, CD39 antigen-like 3, Ecto-ATP diphosphohydrolase 3, Ecto-ATPDase 3, Ecto-ATPase 3, Ecto-apyrase 3, HB6, ENTPD3, CD39L3|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Has a threefold preference for the hydrolysis of ATP over ADP.|
|Cellular Location||Membrane; Multi-pass membrane protein|
|Tissue Location||Expressed in adult brain, pancreas, spleen and prostate. Moderate or low expression is seen in most tissues. Not expressed in liver and peripheral blood leukocytes|
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Provided below are standard protocols that you may find useful for product applications.
ENTPD3 is similar to E-type nucleotidases (NTPases).NTPases, such as CD39, mediate catabolism of extracellularnucleotides. ENTPD3 contains 4 apyrase-conserved regions which ischaracteristic of NTPases.
Fausther, M., et al. Am. J. Physiol. Lung Cell Mol. Physiol. 298 (6), L804-L818 (2010) :Gaddie, K.J., et al. Biochemistry 48(40):9437-9447(2009)Munkonda, M.N., et al. FEBS J. 276(2):479-496(2009)Munkonda, M.N., et al. Biochem. Pharmacol. 74(10):1524-1534(2007)Ivanenkov, V.V., et al. Biochemistry 44(25):8998-9012(2005)
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