TMLHE Antibody (N-term) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q9NVH6 |
---|---|
Clone Names | 91102042 |
Gene ID | 55217 |
---|---|
Other Names | Trimethyllysine dioxygenase, mitochondrial, Epsilon-trimethyllysine 2-oxoglutarate dioxygenase, Epsilon-trimethyllysine hydroxylase, TML hydroxylase, TML-alpha-ketoglutarate dioxygenase, TML dioxygenase, TMLD, TMLHE, TMLH |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | TMLHE |
---|---|
Synonyms | TMLH |
Function | Converts trimethyllysine (TML) into hydroxytrimethyllysine (HTML) (PubMed:11431483, PubMed:23092983). |
Cellular Location | Mitochondrion matrix |
Tissue Location | All isoforms, but isoform 8, are widely expressed in adult and fetal tissues. Isoform 8 is restricted to heart and skeletal muscle. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes the protein trimethyllysine dioxygenasewhich is the first enzyme in the carnitine biosynthesis pathway.Carnitine play an essential role in the transport of activatedfatty acids across the inner mitochondrial membrane. The encodedprotein converts trimethyllysine into hydroxytrimethyllysine. Apseudogene of this gene is found on chromosome X. Alternatesplicing results in multiple transcript variants.
References
Monfregola, J., et al. Gene 395 (1-2), 86-97 (2007) :Monfregola, J., et al. J. Cell. Physiol. 204(3):839-847(2005)Vaz, F.M., et al. J. Biol. Chem. 276(36):33512-33517(2001)Rogner, U.C., et al. Genome Res. 6(10):922-934(1996)
If you have used an Abcepta product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at tech@abcepta.com.