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RDH12 Antibody (N-term) Blocking peptide

Synthetic peptide

Product Information
Primary Accession Q96NR8
Clone Names 91102102
Peptide ID 91102102
Additional Information
Gene ID 145226
Other Names Retinol dehydrogenase 12, 111-, All-trans and 9-cis retinol dehydrogenase, RDH12
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name RDH12
Synonyms SDR7C2
Function Exhibits an oxidoreductive catalytic activity towards retinoids. Most efficient as an NADPH-dependent retinal reductase. Displays high activity toward 9-cis and all-trans-retinol. Also involved in the metabolism of short-chain aldehydes. No steroid dehydrogenase activity detected. Might be the key enzyme in the formation of 11-cis-retinal from 11-cis-retinol during regeneration of the cone visual pigments.
Tissue Location Widely expressed, mostly in eye, kidney, brain, skeletal muscle and stomach
Research Areas
Citations (0)

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The protein encoded by this gene is an NADPH-dependentretinal reductase whose highest activity is toward 9-cis andall-trans-retinol. The encoded enzyme also plays a role in themetabolism of short-chain aldehydes but does not exhibit steroiddehydrogenase activity. Defects in this gene are a cause of Lebercongenital amaurosis type 3 (LCA3).


Clark, G.R., et al. Ophthalmology 117(11):2169-2177(2010)Lee, S.A., et al. FEBS Lett. 584(3):507-510(2010)Marchette, L.D., et al. Free Radic. Biol. Med. 48(1):16-25(2010)Persson, B., et al. Chem. Biol. Interact. 178 (1-3), 94-98 (2009) :Sundaresan, P., et al. Mol. Vis. 15, 1781-1787 (2009) :

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$ 80.00
Cat# BP10748a
(40 western blots)
Availability: In Stock
Bulk Size
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