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TLL1 Antibody (C-term) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | O43897 |
|---|---|
| Clone Names | 91102318 |
| Gene ID | 7092 |
|---|---|
| Other Names | Tolloid-like protein 1, 3424-, TLL1, TLL |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | TLL1 |
|---|---|
| Synonyms | TLL |
| Function | Protease which processes procollagen C-propeptides, such as chordin, pro-biglycan and pro-lysyl oxidase. Required for the embryonic development. Predominant protease, which in the development, influences dorsal-ventral patterning and skeletogenesis. |
| Cellular Location | Secreted. |
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes an astacin-like zinc-dependentmetalloprotease and is a subfamily member of the metzincin family.A similar protein in mice is required during heart development andspecifically processes procollagen C-propeptides and chordin atsimilar cleavage sites.
References
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :Berry, R., et al. FEBS Lett. 584(4):657-661(2010)Sabirzhanova, I.B., et al. Biochem. Biophys. Res. Commun. 389(2):338-342(2009)Stanczak, P., et al. Eur. J. Hum. Genet. 17(3):344-351(2009)Mac Sweeney, A., et al. J. Mol. Biol. 384(1):228-239(2008)
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