|Other Names||Tolloid-like protein 1, 3424-, TLL1, TLL|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Protease which processes procollagen C-propeptides, such as chordin, pro-biglycan and pro-lysyl oxidase. Required for the embryonic development. Predominant protease, which in the development, influences dorsal-ventral patterning and skeletogenesis.|
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Provided below are standard protocols that you may find useful for product applications.
This gene encodes an astacin-like zinc-dependentmetalloprotease and is a subfamily member of the metzincin family.A similar protein in mice is required during heart development andspecifically processes procollagen C-propeptides and chordin atsimilar cleavage sites.
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :Berry, R., et al. FEBS Lett. 584(4):657-661(2010)Sabirzhanova, I.B., et al. Biochem. Biophys. Res. Commun. 389(2):338-342(2009)Stanczak, P., et al. Eur. J. Hum. Genet. 17(3):344-351(2009)Mac Sweeney, A., et al. J. Mol. Biol. 384(1):228-239(2008)
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