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RNT2 Antibody (N-term) Blocking peptide

Synthetic peptide

     
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Product Information
Primary Accession O00584
Clone Names 91109316
Peptide ID 91109316
Additional Information
Gene ID 8635
Other Names Ribonuclease T2, 3127-, Ribonuclease 6, RNASET2, RNASE6PL
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name RNASET2
Synonyms RNASE6PL
Function Has ribonuclease activity, with higher activity at acidic pH. Probably is involved in lysosomal degradation of ribosomal RNA (By similarity). Probably plays a role in cellular RNA catabolism.
Cellular Location Secreted. Lysosome lumen. Endoplasmic reticulum lumen. Note=Subcellular fractionation of transfected ovarian cancer cells reveals full-length RNASET2 in the endoplasmic reticulum fraction and the 2 smaller RNASET2 proteolytic products in the lysosome fraction
Tissue Location Ubiquitous. Higher expression levels observed in the temporal lobe and fetal brain
Research Areas
Citations (0)

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Background

This ribonuclease gene is a novel member of theRh/T2/S-glycoprotein class of extracellular ribonucleases. It is asingle copy gene that maps to 6q27, a region associated with humanmalignancies and chromosomal rearrangement.

References

Fransen, K., et al. Hum. Mol. Genet. 19(17):3482-3488(2010)Quan, C., et al. Nat. Genet. 42(7):614-618(2010)Liu, J., et al. J. Cell. Mol. Med. 14(5):1146-1155(2010)Henneke, M., et al. Nat. Genet. 41(7):773-775(2009)Monti, L., et al. Oncol. Res. 17(2):69-74(2008)

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$ 80.00
Cat# BP10764a
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