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CB086 Antibody (C-term) Blocking peptide

Synthetic peptide

     
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Product Information
Primary Accession O95876
Clone Names 91201024
Peptide ID 91201024
Additional Information
Gene ID 51057
Other Names WD repeat-containing and planar cell polarity effector protein fritz homolog, hFRTZ, Bardet-Biedl syndrome 15 protein, WD repeat-containing and planar cell polarity effector protein, WDPCP, BBS15, C2orf86, FRITZ
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name WDPCP
Synonyms BBS15, C2orf86, FRITZ
Function Probable effector of the planar cell polarity signaling pathway which regulates the septin cytoskeleton in both ciliogenesis and collective cell movements. Together with FUZ and WDPCP proposed to function as core component of the CPLANE (ciliogenesis and planar polarity effectors) complex involved in the recruitment of peripheral IFT-A proteins to basal bodies (By similarity).
Cellular Location Cell membrane {ECO:0000250|UniProtKB:Q32NR9}. Cytoplasm, cytoskeleton, cilium axoneme {ECO:0000250|UniProtKB:Q32NR9}. Cytoplasm, cytoskeleton, cilium basal body {ECO:0000250|UniProtKB:Q32NR9}
Research Areas
Citations (0)

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Background

The C2ORF86 gene encodes an ortholog of Drosophila'fritz,' a cytoplasmic WD40 repeat protein that controls planarcell polarity (summarized by Kim et al., 2010 [PubMed20671153]).

References

Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)Kim, S.K., et al. Science 329(5997):1337-1340(2010)Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)Eeles, R.A., et al. Nat. Genet. 41(10):1116-1121(2009)Melzer, D., et al. PLoS Genet. 4 (5), E1000072 (2008) :

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$ 80.00
Cat# BP10783b
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