|Other Names||La-related protein 6, Acheron, Achn, La ribonucleoprotein domain family member 6, LARP6|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Regulates the coordinated translation of type I collagen alpha-1 and alpha-2 mRNAs, CO1A1 and CO1A2. Stabilizes mRNAs through high-affinity binding of a stem-loop structure in their 5' UTR. This regulation requires VIM and MYH10 filaments, and the helicase DHX9.|
|Cellular Location||Cytoplasm. Nucleus. Note=Shuttles between the nucleus and the cytoplasm|
|Tissue Location||Expressed in numerous tissues.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
email@example.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
LARP6 is a member of the La ribonucleoprotein domain family, which all contain one characteristic La motif. LARP6 shuttles between the cytoplasm and nucleus. It is proposed that members of this family play a role in translation and mRNA stability.
Cai, L., et al. J. Mol. Biol. 395(2):309-326(2010)Glenn, H.L., et al. Am. J. Physiol., Cell Physiol. 298 (1), C46-C55 (2010) :Valavanis, C., et al. Gene 393 (1-2), 101-109 (2007) :Olsen, J.V., et al. Cell 127(3):635-648(2006)Olsen, J.V., et al. Cell 127(3):635-648(2006)
If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at firstname.lastname@example.org.