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MAP1D Antibody (N-term) Blocking peptide

Synthetic peptide

Product Information
Primary Accession Q6UB28
Clone Names 91230228
Peptide ID 91230228
Additional Information
Gene ID 254042
Other Names Methionine aminopeptidase 1D, mitochondrial {ECO:0000255|HAMAP-Rule:MF_03174}, MAP 1D {ECO:0000255|HAMAP-Rule:MF_03174}, MetAP 1D {ECO:0000255|HAMAP-Rule:MF_03174}, 341118 {ECO:0000255|HAMAP-Rule:MF_03174}, Methionyl aminopeptidase type 1D, mitochondrial, Peptidase M 1D {ECO:0000255|HAMAP-Rule:MF_03174}, METAP1D, MAP1D
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms MAP1D
Function Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed (By similarity). May play a role in colon tumorigenesis.
Cellular Location Mitochondrion {ECO:0000255|HAMAP- Rule:MF_03174, ECO:0000269|PubMed:14532271}
Tissue Location Overexpressed in colon cancer cell lines and colon tumors as compared to normal tissues (at protein level)
Research Areas
Citations (0)

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The N-terminal methionine excision pathway is an essentialprocess in which the N-terminal methionine is removed from manyproteins, thus facilitating subsequent protein modification. Inmitochondria, enzymes that catalyze this reaction are celledmethionine aminopeptidases (MetAps, or MAPs; EC (Sereroet al., 2003 [PubMed 14532271]).


Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)Leszczyniecka, M., et al. Oncogene 25(24):3471-3478(2006)Serero, A., et al. J. Biol. Chem. 278(52):52953-52963(2003)

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$ 80.00
Cat# BP10853a
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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