DPY19L1 Antibody (C-term) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q2PZI1 |
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Clone Names | 100107098 |
Gene ID | 23333 |
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Other Names | Probable C-mannosyltransferase DPY19L1, 241-, Dpy-19-like protein 1, Protein dpy-19 homolog 1, DPY19L1, GA0500, KIAA0877 |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | DPY19L1 |
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Synonyms | GA0500, KIAA0877 |
Function | C-mannosyltransferase that mediates the C-mannosylation tryptophan residues on target proteins. The reaction occurs on the luminal side of the endoplasmic reticulum and involves the transfer of a mannose unit from a dolichylphosphate mannose (Dol-P-Man) donor to an acceptor protein containing a WxxW consensus sequence (By similarity). C-mannosylates the first two tryptophans in the WxxWxxWxxC motif in thrombospondin (TSP) type-1 of UNC5A (By similarity). Regulates neurite extension during development (By similarity). |
Cellular Location | Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:A6X919}; Multi-pass membrane protein |
Tissue Location | Widely expressed.. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Belongs to the DPY19 family. There are two named isoforms. The specific function of DPY19L1 is not yet known.
References
Strausberg, R.L., et al. Proc. Natl. Acad. Sci. U.S.A. 99(26):16899-16903(2002)Nagase, T., et al. DNA Res. 5(6):355-364(1998)
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