SIAH3 Antibody (C-term) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q8IW03 |
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Clone Names | 100120156 |
Gene ID | 283514 |
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Other Names | Seven in absentia homolog 3, Siah-3, SIAH3 |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | SIAH3 |
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Function | Negative regulator of PRKN translocation to damaged mitochondria. Acts probably by destabilizing PINK1 protein, hence inhibiting PRKN targeting to dysfunctional depolarized mitochondria. |
Cellular Location | Mitochondrion. |
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Provided below are standard protocols that you may find useful for product applications.
References
Rose, J. Phd, et al. Mol. Med. (2010) In press :
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