|Other Names||Thioredoxin domain-containing protein 8, Spermatid-specific thioredoxin-3, Sptrx-3, Thioredoxin-6, TXNDC8, SPTRX3, TRX6|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||May be required for post-translational modifications of proteins required for acrosomal biogenesis. May act by reducing disulfide bonds within the sperm.|
|Cellular Location||Cytoplasm. Golgi apparatus|
|Tissue Location||Testis-specific. Only expressed during spermiogenesis, prominently in the Golgi apparatus of pachytene spermatocytes and round and elongated spermatids, with a transient localization in the developing acrosome of round spermatids (at protein level).|
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May be required for post-translational modifications of proteins required for acrosomal biogenesis. May act by reducing disulfide bonds within the sperm.
Jimenez, A., et al. J. Biol. Chem. 279(33):34971-34982(2004)Humphray, S.J., et al. Nature 429(6990):369-374(2004)
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