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TBC14 Antibody (Center) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q9P2M4 |
|---|---|
| Clone Names | 91113306 |
| Gene ID | 57533 |
|---|---|
| Other Names | TBC1 domain family member 14, TBC1D14, KIAA1322 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | TBC1D14 |
|---|---|
| Synonyms | KIAA1322 |
| Function | Plays a role in the regulation of starvation-induced autophagosome formation (PubMed:22613832). Together with the TRAPPIII complex, regulates a constitutive trafficking step from peripheral recycling endosomes to the early Golgi, maintaining the cycling pool of ATG9 required for initiation of autophagy. |
| Cellular Location | Golgi apparatus, cis-Golgi network. Golgi apparatus, trans-Golgi network Note=After amino acid starvation, Golgi apparatus-associated protein levels increase compared with fed conditions. May be cycling between the Golgi apparatus and an endosomal pool, redistributing to the Golgi apparatus upon starvation |
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Provided below are standard protocols that you may find useful for product applications.
Background
May act as a GTPase-activating protein for Rab family protein(s) (By similarity).
References
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :Ishibashi, K., et al. Genes Cells 14(1):41-52(2009)Tempel, W., et al. Proteins 71(1):497-502(2008)
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