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PPM1L Antibody (C-term) Blocking peptide

Synthetic peptide

Product Information
Primary Accession Q5SGD2
Clone Names 91119075
Peptide ID 91119075
Additional Information
Gene ID 151742
Other Names Protein phosphatase 1L, Protein phosphatase 1-like, Protein phosphatase 2C isoform epsilon, PP2C-epsilon, PPM1L, PP2CE
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name PPM1L
Synonyms PP2CE
Function Acts as a suppressor of the SAPK signaling pathways by associating with and dephosphorylating MAP3K7/TAK1 and MAP3K5, and by attenuating the association between MAP3K7/TAK1 and MAP2K4 or MAP2K6.
Cellular Location Membrane; Single-pass type I membrane protein
Tissue Location Ubiquitous. Highly expressed in heart, placenta, lung, liver, kidney and pancreas
Research Areas
Citations (0)

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PPM1L, or PP2CE, belongs to the PP2C group ofserine/threonine phosphatases, which are distinguished from otherphosphatases by their structure, absolute requirement for Mg(2+) orMn(2+), and insensitivity to okadaic acid. PP2Cs regulatestress-activated protein kinase (SAPK; see MIM 601158) signalingcascades that respond to extracellular stimuli (Jin et al., 2004[PubMed 15560375]).


Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :Thean, L.F., et al. Genes Chromosomes Cancer 49(2):99-106(2010)Trynka, G., et al. Gut 58(8):1078-1083(2009)Saito, S., et al. J. Biol. Chem. 283(10):6584-6593(2008)Saito, J., et al. Biochem. J. 405(3):591-596(2007)

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$ 80.00
Cat# BP11001b
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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