ACN9 Antibody (N-term) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q9NRP4 |
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Other Accession | NP_064571.1 |
Clone Names | 91201005 |
Gene ID | 57001 |
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Other Names | Succinate dehydrogenase assembly factor 3, mitochondrial, ACN9 (HGNC:21752) |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | SDHAF3 (HGNC:21752) |
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Function | Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Promotes maturation of the iron-sulfur protein subunit SDHB of the SDH catalytic dimer, protecting it from the deleterious effects of oxidants. May act together with SDHAF1. |
Cellular Location | Mitochondrion matrix {ECO:0000250|UniProtKB:Q04401} |
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Provided below are standard protocols that you may find useful for product applications.
References
Bailey, S.D., et al. Diabetes Care (2010) In press :Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)Dick, D.M., et al. Biol. Psychiatry 63(11):1047-1053(2008)Dennis, R.A., et al. Eur. J. Biochem. 261(1):236-243(1999)
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