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>   home   >   Products   >   Peptides   >   Blocking Peptides   >   CYP2B6 Antibody (Center) Blocking peptide   

CYP2B6 Antibody (Center) Blocking peptide

Synthetic peptide

Product Information
Primary Accession P20813
Clone Names 80305195
Peptide ID 80305195
Additional Information
Gene ID 1555
Other Names Cytochrome P450 2B6, 11413-, 4-cineole 2-exo-monooxygenase, CYPIIB6, Cytochrome P450 IIB1, CYP2B6
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name CYP2B6
Function Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. Acts as a 1,4-cineole 2-exo-monooxygenase.
Cellular Location Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein
Tissue Location Expressed in liver, lung and heart right ventricle.
Research Areas
Citations (0)

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This gene, CYP2B6, encodes a member of the cytochrome P450superfamily of enzymes. The cytochrome P450 proteins aremonooxygenases which catalyze many reactions involved in drugmetabolism and synthesis of cholesterol, steroids and other lipids.This protein localizes to the endoplasmic reticulum and itsexpression is induced by phenobarbital. The enzyme is known tometabolize some xenobiotics, such as the anti-cancer drugscyclophosphamide and ifosphamide. Transcript variants for this genehave been described; however, it has not been resolved whetherthese transcripts are in fact produced by this gene or by a closelyrelated pseudogene, CYP2B7. Both the gene and the pseudogene arelocated in the middle of a CYP2A pseudogene found in a largecluster of cytochrome P450 genes from the CYP2A, CYP2B and CYP2Fsubfamilies on chromosome 19q.


Figueroa, S.C., et al. Ther Drug Monit 32(5):579-585(2010)Chou, M., et al. Antimicrob. Agents Chemother. 54(10):4432-4439(2010)Shimada, M., et al. Hum. Genet. 128(4):433-441(2010)Bunten, H., et al. Clin. Pharmacol. Ther. 88(3):383-389(2010)Gounden, V., et al. AIDS Res Ther 7, 32 (2010) :

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$ 80.00
Cat# BP11104c
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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