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EMG1 Antibody (Center) Blocking peptide

Synthetic peptide

Product Information
Primary Accession Q92979
Clone Names 90909044
Peptide ID 90909044
Additional Information
Gene ID 10436
Other Names Ribosomal RNA small subunit methyltransferase NEP1, 211-, 18S rRNA (pseudouridine(1248)-N1)-methyltransferase, 18S rRNA Psi1248 methyltransferase, Nucleolar protein EMG1 homolog, Protein C2f, Ribosome biogenesis protein NEP1, EMG1 {ECO:0000303|PubMed:19463982}
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name EMG1 {ECO:0000303|PubMed:19463982}
Function S-adenosyl-L-methionine-dependent pseudouridine N(1)- methyltransferase that methylates pseudouridine at position 1248 (Psi1248) in 18S rRNA. Involved the biosynthesis of the hypermodified N1-methyl-N3-(3-amino-3-carboxypropyl) pseudouridine (m1acp3-Psi) conserved in eukaryotic 18S rRNA. Is not able to methylate uridine at this position (PubMed:20047967). Has also an essential role in 40S ribosomal subunit biogenesis independent on its methyltransferase activity, facilitating the incorporation of ribosomal protein S19 during the formation of pre-ribosomes (By similarity).
Cellular Location Nucleus, nucleolus
Research Areas
Citations (0)

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This gene encodes an essential, conserved eukaryoticprotein involved in ribosome biogenesis. In yeast, the relatedprotein is a component of the small subunit processome and isessential for biogenesis of the ribosomal 40S subunit. A mutationin this gene has been associated with Bowen-Conradi syndrome.


Armistead, J., et al. Am. J. Hum. Genet. 84(6):728-739(2009)Lamesch, P., et al. Genomics 89(3):307-315(2007)Lamont, R.E., et al. Am. J. Med. Genet. A 132A (2), 136-143 (2005) :Bernstein, K.A., et al. Eukaryotic Cell 3(6):1619-1626(2004)Eschrich, D., et al. Curr. Genet. 40(5):326-338(2002)

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$ 80.00
Cat# BP11129c
Availability: In Stock
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