|Other Names||Guanine nucleotide exchange factor MSS4, Rab-interacting factor, RABIF, MSS4, RASGRF3|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Guanine-nucleotide-releasing protein that acts on members of the SEC4/YPT1/RAB subfamily. Stimulates GDP release from both YPT1 and RAB3A, but is less active on these proteins than on the SEC4 protein. Might play a general role in vesicular transport.|
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Provided below are standard protocols that you may find useful for product applications.
The Sec4/Rab-related small GTP-binding proteins areinvolved in the regulation of intracellular vesicular transport.Mss4 stimulates GTP-GDP exchange in Sec4 and Rab and binds to asubset of genetically related Rab proteins.
Ehret, G.B., et al. Eur. J. Hum. Genet. 17(12):1650-1657(2009)Stelzl, U., et al. Cell 122(6):957-968(2005)Strick, D.J., et al. J. Biol. Chem. 277(36):32722-32729(2002)Wixler, V., et al. FEBS Lett. 445 (2-3), 351-355 (1999) :Muller-Pillasch, F., et al. Genomics 46(3):389-396(1997)
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