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HMOX1 Antibody (Center) Blocking peptide

Synthetic peptide

Product Information
Primary Accession P09601
Clone Names 90625088
Peptide ID 90625088
Additional Information
Gene ID 3162
Other Names Heme oxygenase 1, HO-1, HMOX1, HO, HO1
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name HMOX1
Synonyms HO, HO1
Function Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. Under physiological conditions, the activity of heme oxygenase is highest in the spleen, where senescent erythrocytes are sequestrated and destroyed. Exhibits cytoprotective effects since excess of free heme sensitizes cells to undergo apoptosis.
Cellular Location Microsome. Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side
Tissue Location Expressed at higher levels in renal cancer tissue than in normal tissue (at protein level)
Research Areas
Citations (0)

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Heme oxygenase, an essential enzyme in heme catabolism,cleaves heme to form biliverdin, which is subsequently converted tobilirubin by biliverdin reductase, and carbon monoxide, a putativeneurotransmitter. Heme oxygenase activity is induced by itssubstrate heme and by various nonheme substances. Heme oxygenaseoccurs as 2 isozymes, an inducible heme oxygenase-1 and aconstitutive heme oxygenase-2. HMOX1 and HMOX2 belong to the hemeoxygenase family.


Wu, M.M., et al. Toxicol. Appl. Pharmacol. 248(3):226-233(2010)Bolisetty, S., et al. J. Am. Soc. Nephrol. 21(10):1702-1712(2010)Bao, W., et al. PLoS ONE 5 (8), E12371 (2010) :Wu, M.M., et al. J. Biomed. Sci. 17, 70 (2010) :Wang, X., et al. PLoS ONE 5 (8), E11934 (2010) :

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$ 80.00
Cat# BP11240c
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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