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NR6A1 Antibody (N-term) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q15406 |
|---|---|
| Clone Names | 70716056 |
| Gene ID | 2649 |
|---|---|
| Other Names | Nuclear receptor subfamily 6 group A member 1, Germ cell nuclear factor, GCNF, hGCNF, Retinoid receptor-related testis-specific receptor, RTR, hRTR, NR6A1, GCNF |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | NR6A1 |
|---|---|
| Synonyms | GCNF |
| Function | Orphan nuclear receptor. Binds to a response element containing the sequence 5'-TCAAGGTCA-3'. May be involved in the regulation of gene expression in germ cell development during gametogenesis (By similarity). |
| Cellular Location | Nucleus. |
| Tissue Location | Shows highest expression in the germ cells of the adult testis. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes an orphan nuclear receptor which is amember of the nuclear hormone receptor family. Its expressionpattern suggests that it may be involved in neurogenesis and germcell development. The protein can homodimerize and bind DNA, but invivo targets have not been identified. The gene expresses at leastalternatively spliced transcript variants.
References
Letra, A., et al. Am. J. Med. Genet. A 152A (7), 1701-1710 (2010) :Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :Rajkovic, M., et al. J. Biol. Chem. 279(50):52493-52499(2004)Yang, G., et al. Biol. Reprod. 68(5):1620-1630(2003)Lan, Z.J., et al. J. Biol. Chem. 277(52):50660-50667(2002)
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