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MFS10 Antibody (Center) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q14728 |
|---|---|
| Clone Names | 91208090 |
| Gene ID | 10227 |
|---|---|
| Other Names | Major facilitator superfamily domain-containing protein 10, Tetracycline transporter-like protein, MFSD10, TETRAN |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | MFSD10 |
|---|---|
| Synonyms | TETRAN |
| Function | Probable organic anion transporter which may serve as a transporter for some non-steroidal anti-inflammatory drugs (NSAIDs) as well as other organic anions across the luminal membranes of renal proximal tubules at the final excretion step into the urine. |
| Cellular Location | Nucleus inner membrane {ECO:0000250|UniProtKB:Q9D2V8}; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein |
| Tissue Location | Expressed in luminal membrane of renal tubules (at protein level) (PubMed:18638446). Detected in all tissues tested with higher expression in heart, splee, kidney, leukocytes and prostate (PubMed:18638446). |
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes a member of the major facilitatorsuperfamily of transporter proteins. The encoded protein likelyfunctions in efflux of organic anions, including the non-steroidalanti-inflammatory drugs indomethacin and diclofenac. Alternativelyspliced transcript variants have been described. [provided byRefSeq].
References
Ushijima, H., et al. Biochem. Biophys. Res. Commun. 374(2):325-330(2008)Mima, S., et al. FEBS Lett. 581(7):1457-1463(2007)Duyao, M.P., et al. Hum. Mol. Genet. 2(6):673-676(1993)
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