|Other Names||Major facilitator superfamily domain-containing protein 10, Tetracycline transporter-like protein, MFSD10, TETRAN|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Confers cellular resistance to apoptosis induced by the non-steroidal anti-inflammatory drugs indomethacin and diclofenac. May act as an efflux pump.|
|Cellular Location||Membrane; Multi-pass membrane protein|
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This gene encodes a member of the major facilitatorsuperfamily of transporter proteins. The encoded protein likelyfunctions in efflux of organic anions, including the non-steroidalanti-inflammatory drugs indomethacin and diclofenac. Alternativelyspliced transcript variants have been described. [provided byRefSeq].
Ushijima, H., et al. Biochem. Biophys. Res. Commun. 374(2):325-330(2008)Mima, S., et al. FEBS Lett. 581(7):1457-1463(2007)Duyao, M.P., et al. Hum. Mol. Genet. 2(6):673-676(1993)
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