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A2LD1 Antibody (C-term) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q9BVM4 |
|---|---|
| Clone Names | 100126050 |
| Gene ID | 87769 |
|---|---|
| Other Names | Gamma-glutamylaminecyclotransferase, GGACT, AIG2-like domain-containing protein 1, Gamma-glutamylamine cyclotransferase, GGACT, A2LD1 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | GGACT |
|---|---|
| Synonyms | A2LD1 |
| Function | Contributes to degradation of proteins cross-linked by transglutaminases by degrading the cross-link between a lysine and a glutamic acid residue. Catalyzes the formation of 5-oxo-L-proline from L-gamma-glutamyl-L-epsilon-lysine. Inactive with L-gamma-glutamyl- alpha-amino acid substrates such as L-gamma-glutamyl-L-alpha-cysteine and L-gamma-glutamyl-L-alpha-alanine. |
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Provided below are standard protocols that you may find useful for product applications.
Background
The protein encoded by this gene aids in the proteolyticdegradation of crosslinked fibrin by breaking down isodipeptideL-gamma-glutamyl-L-epsilon-lysine, a byproduct of fibrindegradation. The reaction catalyzed by the encodedgamma-glutamylaminecyclotransferase produces 5-oxo-L-proline and afree alkylamine. Two transcript variants encoding the same proteinhave been found for this gene.
References
Oakley, A.J., et al. J. Biol. Chem. 285(13):9642-9648(2010)
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