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GMIP Antibody (C-term) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q9P107 |
|---|---|
| Clone Names | 91201204 |
| Gene ID | 51291 |
|---|---|
| Other Names | GEM-interacting protein, GMIP, GMIP |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | GMIP |
|---|---|
| Function | Stimulates, in vitro and in vivo, the GTPase activity of RhoA. |
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes a member of the ARHGAP family ofRho/Rac/Cdc42-like GTPase activating proteins. The encoded proteininteracts with the Ras-related protein Gem through its N-terminaldomain. Separately, it interacts with RhoA through a RhoGAP domain,and stimulates RhoA-dependent GTPase activity. Alternativelyspliced variants that encode different protein isoforms have beendescribed but their full-length nature has not been determined.
References
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)Bosker, F.J., et al. Mol. Psychiatry (2010) In press :Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)Deng, Y.J., et al. Mol. Immunol. 43(9):1497-1507(2006)Tadokoro, K., et al. Neurogenetics 6(3):127-133(2005)
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