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C2orf43 Antibody (C-term) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q9H6V9 |
|---|---|
| Clone Names | 100408274 |
| Gene ID | 60526 |
|---|---|
| Other Names | UPF0554 protein C2orf43, C2orf43 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | LDAH {ECO:0000303|PubMed:24357060, ECO:0000312|HGNC:HGNC:26145} |
|---|---|
| Function | Probable serine lipid hydrolase associated with lipid droplets. Appears to lack cholesterol esterase activity. Appears to lack triglyceride lipase activity. Highly expressed in macrophage-rich areas in atherosclerotic lesions, suggesting that it could promote cholesterol ester turnover in macrophages. |
| Cellular Location | Lipid droplet. Endoplasmic reticulum {ECO:0000250|UniProtKB:Q8BVA5}. Note=Localizes to the endoplasmic reticulum in absence of lipid droplets and translocates to lipid droplets upon lipid storage induction {ECO:0000250|UniProtKB:Q8BVA5} |
| Tissue Location | Present in macrophage-rich areas in atherosclerotic lesionsv(at protein level). |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
The specific function of the protein remains unknown.
References
Takata, R., et al. Nat. Genet. 42(9):751-754(2010)Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :Barber, M.J., et al. PLoS ONE 5 (3), E9763 (2010) :Aulchenko, Y.S., et al. Nat. Genet. 41(1):47-55(2009)Kathiresan, S., et al. Nat. Genet. 41(1):56-65(2009)
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