|Other Names||Probetacellulin, Betacellulin, BTC, BTC|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Growth factor that binds to EGFR, ERBB4 and other EGF receptor family members. Potent mitogen for retinal pigment epithelial cells and vascular smooth muscle cells.|
|Cellular Location||Betacellulin: Secreted, extracellular space.|
|Tissue Location||Synthesized in several tissues and tumor cells. Predominantly expressed in pancreas and small intestine|
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Provided below are standard protocols that you may find useful for product applications.
This gene encodes a protein which induces ectopic boneformation in conjunction with transforming growth factor beta. Thisprotein is a small proteoglycan which contains tandem leucine-richrepeats (LRR). Alternatively spliced transcript variants thatencode the same protein have been found for this gene. [provided byRefSeq].
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :Dimasi, D.P., et al. Mol. Vis. 16, 562-569 (2010) :Yerges, L.M., et al. J. Bone Miner. Res. 24(12):2039-2049(2009)Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
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