|Other Names||Paired box protein Pax-5, B-cell-specific transcription factor, BSAP, PAX5|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||May play an important role in B-cell differentiation as well as neural development and spermatogenesis. Involved in the regulation of the CD19 gene, a B-lymphoid-specific target gene.|
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Provided below are standard protocols that you may find useful for product applications.
Lysophospholipases are enzymes that act on biologicalmembranes to regulate the multifunctional lysophospholipids. Theprotein encoded by this gene hydrolyzes lysophosphatidylcholine toglycerophosphorylcholine and a free fatty acid. This enzyme ispresent in the plasma and thought to be associated withhigh-density lipoprotein. A later paper contradicts the function ofthis gene. It demonstrates that this gene encodes a lysosomalenzyme instead of a lysophospholipase and has bothcalcium-independent phospholipase A2 and transacylase activities.
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)Cucchiara, B.L., et al. Stroke 40(7):2332-2336(2009)Hoffmann, M.M., et al. J. Thromb. Haemost. 7(1):41-48(2009)Schaloske, R.H., et al. Biochim. Biophys. Acta 1761(11):1246-1259(2006)
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