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>   home   >   Products   >   Peptides   >   Blocking Peptides   >   TMEM100 Antibody (C-term) Blocking peptide   

TMEM100 Antibody (C-term) Blocking peptide

Synthetic peptide

Product Information
Primary Accession Q9NV29
Other Accession NP_001093110.1, NP_060756.2
Clone Names 91216032
Peptide ID 91216032
Additional Information
Gene ID 55273
Other Names Transmembrane protein 100, TMEM100
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name TMEM100
Function Plays a role during embryonic arterial endothelium differentiation and vascular morphogenesis through the ACVRL1 receptor-dependent signaling pathway upon stimulation by bone morphogenetic proteins, such as GDF2/BMP9 and BMP10. Involved in the regulation of nociception, acting as a modulator of the interaction between TRPA1 and TRPV1, two molecular sensors and mediators of pain signals in dorsal root ganglia (DRG) neurons. Mechanistically, it weakens their interaction, thereby releasing the inhibition of TRPA1 by TRPV1 and increasing the single-channel open probability of the TRPA1-TRPV1 complex.
Cellular Location Cell membrane; Multi-pass membrane protein. Membrane; Multi-pass membrane protein Perikaryon. Cytoplasm, perinuclear region. Endoplasmic reticulum Note=Colocalized with HSPA5 in the endoplasmic reticulum (ER) Enriched in ER microsome. Colocalized with BMP4 in neural cell bodies and neural fibers of the enteric nervous system
Tissue Location Expressed in neurons of the myenteric and submucosal plexuses in the gastric body, jejunum and proximal colon. Expressed in arterial endothelial cells and neurons of the central nervous system and peripheral nervous system. Expressed in umbilical artery endothelial cells (at protein level)
Research Areas
Citations (0)

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Grozdanov, P.N., et al. RNA 15(6):1188-1197(2009)

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$ 80.00
Cat# BP11713b
Availability: In Stock
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