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SYUG Antibody (C-term) Blocking peptide

Synthetic peptide

     
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Product Information
Primary Accession O76070
Other Accession NP_003078.2
Clone Names 80821049
Additional Information
Gene ID 6623
Other Names Gamma-synuclein, Breast cancer-specific gene 1 protein, Persyn, Synoretin, SR, SNCG, BCSG1, PERSYN, PRSN
Format Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name SNCG
Synonyms BCSG1, PERSYN, PRSN
Function Plays a role in neurofilament network integrity. May be involved in modulating axonal architecture during development and in the adult. In vitro, increases the susceptibility of neurofilament-H to calcium-dependent proteases (By similarity). May also function in modulating the keratin network in skin. Activates the MAPK and Elk-1 signal transduction pathway (By similarity).
Cellular Location Cytoplasm, perinuclear region. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle. Note=Associated with centrosomes in several interphase cells. In mitotic cells, localized to the poles of the spindle
Tissue Location Highly expressed in brain, particularly in the substantia nigra. Also expressed in the corpus callosum, heart, skeletal muscle, ovary, testis, colon and spleen. Weak expression in pancreas, kidney and lung
Research Areas
Citations (0)
citation

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Background

Major glycoprotein component of a variety of mucus gels. Thought to provide a protective, lubricating barrier against particles and infectious agents at mucosal surfaces (By similarity).

References

Li, M., et al. J. Biol. Chem. 285(40):30480-30488(2010)Nishioka, K., et al. Arch. Neurol. 67(8):970-975(2010)Ye, Q., et al. Oncol. Rep. 23(2):429-436(2010)Ye, Q., et al. World J. Gastroenterol. 15(40):5035-5043(2009)Hu, H., et al. Clin. Cancer Res. 15(17):5485-5493(2009)

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$ 277.78
Cat# BP11775b
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Availability: 2 weeks
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