SYUG Antibody (C-term) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | O76070 |
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Other Accession | NP_003078.2 |
Clone Names | 80821049 |
Gene ID | 6623 |
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Other Names | Gamma-synuclein, Breast cancer-specific gene 1 protein, Persyn, Synoretin, SR, SNCG, BCSG1, PERSYN, PRSN |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | SNCG |
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Synonyms | BCSG1, PERSYN, PRSN |
Function | Plays a role in neurofilament network integrity. May be involved in modulating axonal architecture during development and in the adult. In vitro, increases the susceptibility of neurofilament-H to calcium-dependent proteases (By similarity). May also function in modulating the keratin network in skin. Activates the MAPK and Elk-1 signal transduction pathway (By similarity). |
Cellular Location | Cytoplasm, perinuclear region. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle. Note=Associated with centrosomes in several interphase cells. In mitotic cells, localized to the poles of the spindle |
Tissue Location | Highly expressed in brain, particularly in the substantia nigra. Also expressed in the corpus callosum, heart, skeletal muscle, ovary, testis, colon and spleen. Weak expression in pancreas, kidney and lung |
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Provided below are standard protocols that you may find useful for product applications.
Background
Major glycoprotein component of a variety of mucus gels. Thought to provide a protective, lubricating barrier against particles and infectious agents at mucosal surfaces (By similarity).
References
Li, M., et al. J. Biol. Chem. 285(40):30480-30488(2010)Nishioka, K., et al. Arch. Neurol. 67(8):970-975(2010)Ye, Q., et al. Oncol. Rep. 23(2):429-436(2010)Ye, Q., et al. World J. Gastroenterol. 15(40):5035-5043(2009)Hu, H., et al. Clin. Cancer Res. 15(17):5485-5493(2009)
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