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CMGA Antibody (C-term) Blocking peptide

Synthetic peptide

Product Information
Primary Accession P10645
Clone Names 80808024
Peptide ID 80808024
Additional Information
Gene ID 1113
Other Names Chromogranin-A, CgA, Pituitary secretory protein I, SP-I, Vasostatin-1, Vasostatin I, Vasostatin-2, Vasostatin II, EA-92, ES-43, Pancreastatin, SS-18, WA-8, WE-14, LF-19, AL-11, GV-19, GR-44, ER-37, CHGA
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Function Pancreastatin: Strongly inhibits glucose induced insulin release from the pancreas. Serpinin: Regulates granule biogenesis in endocrine cells by up-regulating the transcription of protease nexin 1 (SERPINE2) via a cAMP-PKA-SP1 pathway. This leads to inhibition of granule protein degradation in the Golgi complex which in turn promotes granule formation.
Cellular Location Cytoplasmic vesicle, secretory vesicle lumen. Cytoplasmic vesicle, secretory vesicle membrane. Secreted. Note=Associated with the secretory granule membrane through direct interaction to SCG3 that in turn binds to cholesterol-enriched lipid rafts in intragranular conditions.
Tissue Location GE-25 is found in the brain.
Research Areas
Citations (0)

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This gene is a member of the BCL2/adenovirus E1B 19kd-interacting protein (BNIP) family. It interacts with the E1B 19kDa protein which is responsible for the protection ofvirally-induced cell death, as well as E1B 19 kDa-like sequences ofBCL2, also an apoptotic protector. The protein encoded by thisgene is a functional homolog of BNIP3, a proapoptotic protein.This protein may function simultaneously with BNIP3 and may play arole in tumor suppression.


Novak, I., et al. EMBO Rep. 11(1):45-51(2010)Bellot, G., et al. Mol. Cell. Biol. 29(10):2570-2581(2009)Wang, L., et al. Cancer Epidemiol. Biomarkers Prev. 17(12):3558-3566(2008)Papandreou, I., et al. Cell Death Differ. 15(10):1572-1581(2008)Liu, W., et al. Neoplasia 10(8):897-907(2008)

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$ 80.00
Cat# BP11784b
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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Ordering Information

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