Foundational characteristics of cancer include proliferation, angiogenesis, migration, evasion of apoptosis, and cellular immortality. Find key markers for these cellular processes and antibodies to detect them.
The SUMOplot™ Analysis Program predicts and scores sumoylation sites in your protein. SUMOylation is a post-translational modification involved in various cellular processes, such as nuclear-cytosolic transport, transcriptional regulation, apoptosis, protein stability, response to stress, and progression through the cell cycle.
The Autophagy Receptor Motif Plotter predicts and scores autophagy receptor binding sites in your protein. Identifying proteins connected to this pathway is critical to understanding the role of autophagy in physiological as well as pathological processes such as development, differentiation, neurodegenerative diseases, stress, infection, and cancer.
PRR19 Antibody (Center) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | A6NJB7 |
|---|---|
| Clone Names | 100408149 |
| Gene ID | 284338 |
|---|---|
| Other Names | Proline-rich protein 19, PRR19 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | PRR19 (HGNC:33728) |
|---|---|
| Function | Promotes meiotic crossing over formation through its interaction with CNTD1 by participating in the crossover differentiation step of crossover-specific recombination intermediates. |
| Cellular Location | Nucleus {ECO:0000250|UniProtKB:B2RW88}. Chromosome {ECO:0000250|UniProtKB:B2RW88}. Note=Co-localized at crossover sites with CNTD1. Localizes on synapsed chromosome only in mid/late pachytene spermatocytes. {ECO:0000250|UniProtKB:B2RW88} |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Background
Cholesterol homeostasis is regulated, at least in part, bysterol regulatory element (SRE)-binding proteins (e.g., SREBP1; MIM184756) and by liver X receptors (e.g., LXRA; MIM 602423). Uponsterol depletion, LXRs are inactive and SREBPs are cleaved, afterwhich they bind promoter SREs and activate genes involved incholesterol biosynthesis and uptake. Sterol transport is mediatedby vesicles or by soluble protein carriers, such as steroidogenicacute regulatory protein (STAR; MIM 600617). STAR is homologous toa family of proteins containing a 200- to 210-amino acidSTAR-related lipid transfer (START) domain, including STARD6(Soccio et al., 2002 [PubMed 12011452]).
References
Bailey, S.D., et al. Diabetes Care (2010) In press :Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)Soccio, R.E., et al. Proc. Natl. Acad. Sci. U.S.A. 99(10):6943-6948(2002)
If you have used an Abcepta product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at tech@abcepta.com.
Ordering Information
Other Products
Shipping Information
