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ROPN1L Antibody (N-term) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q96C74 |
|---|---|
| Clone Names | 100126185 |
| Gene ID | 83853 |
|---|---|
| Other Names | Ropporin-1-like protein, ROPN1-like protein, AKAP-associated sperm protein, ROPN1L, ASP |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | ROPN1L |
|---|---|
| Synonyms | ASP, RSPH11 {ECO:0000303|PubMed:27120127 |
| Function | Functions as part of axonemal radial spoke complexes that play an important part in the motility of sperm and cilia. Important for male fertility. With ROPN1, involved in fibrous sheath integrity and sperm motility, plays a role in PKA-dependent signaling processes required for spermatozoa capacitation. |
| Cellular Location | Cell projection, cilium, flagellum {ECO:0000250|UniProtKB:Q9EQ00}. Cell projection, cilium |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Cyclic nucleotide phosphodiesterases (PDEs) catalyzehydrolysis of the cyclic nucleotides cAMP and cGMP to thecorresponding nucleoside 5-prime-monophosphates. Mammalian PDEshave been classified into several families based on theirbiochemical properties. Members of the PDE1 family, such as PDE1B,are calmodulin (see MIM 114180)-dependent PDEs (CaM-PDEs) that arestimulated by a calcium-calmodulin complex (Repaske et al., 1992[PubMed 1326532]).
References
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)Vandeput, F., et al. J. Biol. Chem. 282(45):32749-32757(2007)Bender, A.T., et al. Proc. Natl. Acad. Sci. U.S.A. 103(2):460-465(2006)Bender, A.T., et al. Proc. Natl. Acad. Sci. U.S.A. 102(2):497-502(2005)
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