|Other Names||Calcium/calmodulin-dependent 3', 5'-cyclic nucleotide phosphodiesterase 1B, Cam-PDE 1B, 63 kDa Cam-PDE, PDE1B, PDE1B1, PDES1B|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Cyclic nucleotide phosphodiesterase with a dual- specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes. Has a preference for cGMP as a substrate.|
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The protein encoded by this intronless gene belongs to theGSK-3-binding protein family. Studies show that this protein playsa role as a positive regulator of the WNT signaling pathway. It maybe upregulated in tumor progression.
Lee, D.Y., et al. Menopause 17(5):1064-1070(2010)Liu, G.P., et al. Neurobiol. Aging 29(9):1348-1358(2008)Stoothoff, W.H., et al. J. Biol. Chem. 280(1):270-276(2005)Deloukas, P., et al. Nature 429(6990):375-381(2004)Freemantle, S.J., et al. Gene 291 (1-2), 17-27 (2002) :
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