|Other Names||Protein phosphatase 1 regulatory subunit 17, G-substrate, PPP1R17, C7orf16, GSBS|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Inhibits phosphatase activities of protein phosphatase 1 (PP1) and protein phosphatase 2A (PP2A) complexes.|
|Tissue Location||Highly expressed in cerebellum.|
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Involved in cell-matrix and cell-cell adhesion interactions that are required for normal development. May participate in the linkage between muscle fiber and basement membrane. May play a role in endochondral ossification of bone and branching morphogenesis of lung. Binds heparin.
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :Ono, S., et al. J. Hum. Genet. 48(9):447-450(2003)Endo, S., et al. Proc. Natl. Acad. Sci. U.S.A. 96(5):2467-2472(1999)Hall, K.U., et al. J. Biol. Chem. 274(6):3485-3495(1999)
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