|Other Names||NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial, Complex I-SGDH, CI-SGDH, NADH-ubiquinone oxidoreductase SGDH subunit, NDUFB5|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.|
|Cellular Location||Mitochondrion inner membrane; Single-pass membrane protein; Matrix side|
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Provided below are standard protocols that you may find useful for product applications.
The protein encoded by this gene is a subunit of themultisubunit NADH:ubiquinone oxidoreductase (complex I). Mammaliancomplex I is composed of 45 different subunits. It locates at themitochondrial inner membrane. This protein has NADH dehydrogenaseactivity and oxidoreductase activity. It transfers electrons fromNADH to the respiratory chain. The immediate electron acceptor forthe enzyme is believed to be ubiquinone.
Saito, A., et al. J. Hum. Genet. 54(6):317-323(2009)Martins-de-Souza, D., et al. J Neural Transm 116(3):275-289(2009)Wang, L., et al. Cancer Epidemiol. Biomarkers Prev. 17(12):3558-3566(2008)Starr, J.M., et al. Mech. Ageing Dev. 129(12):745-751(2008)Lamesch, P., et al. Genomics 89(3):307-315(2007)
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