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FLJ23356 Antibody (C-term) Blocking peptide

Synthetic peptide

Product Information
Primary Accession Q9H5K3
Clone Names 50908284
Peptide ID 50908284
Additional Information
Gene ID 84197
Other Names Protein O-mannose kinase, POMK, Protein kinase-like protein SgK196, Sugen kinase 196, POMK, SGK196
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms SGK196
Function Protein O-mannose kinase that specifically mediates phosphorylation at the 6-position of an O-mannose of the trisaccharide (N-acetylgalactosamine (GalNAc)-beta-1,3-N- acetylglucosamine (GlcNAc)-beta-1,4-mannose) to generate phosphorylated O-mannosyl trisaccharide (N-acetylgalactosamine- beta-1,3-N-acetylglucosamine-beta-1,4-(phosphate-6-)mannose). Phosphorylated O-mannosyl trisaccharide is a carbohydrate structure present in alpha-dystroglycan (DAG1), which is required for binding laminin G-like domain-containing extracellular proteins with high affinity. Only shows kinase activity when the GalNAc-beta-3-GlcNAc-beta-terminus is linked to the 4-position of O-mannose, suggesting that this disaccharide serves as the substrate recognition motif.
Cellular Location Endoplasmic reticulum membrane; Single-pass type II membrane protein
Tissue Location Highest expression is observed in brain, skeletal muscle, kidney and heart in fetal and adult tissues
Research Areas
Citations (0)

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SGK196 belongs to the protein kinase superfamily. Ser/Thr protein kinase family. STKL subfamily


Barrios-Rodiles, M., et al. Science 307(5715):1621-1625(2005)

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$ 80.00
Cat# BP11865b
(40 western blots)
Availability: In Stock
Bulk Size
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