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TNFSF15 Antibody (Center) Blocking peptide

Synthetic peptide

Product Information
Primary Accession O95150
Clone Names 90713219
Peptide ID 90713219
Additional Information
Gene ID 9966
Other Names Tumor necrosis factor ligand superfamily member 15, TNF ligand-related molecule 1, Vascular endothelial cell growth inhibitor, Tumor necrosis factor ligand superfamily member 15, membrane form, Tumor necrosis factor ligand superfamily member 15, secreted form, TNFSF15, TL1, VEGI
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name TNFSF15
Synonyms TL1, VEGI
Function Receptor for TNFRSF25 and TNFRSF6B. Mediates activation of NF-kappa-B. Inhibits vascular endothelial growth and angiogenesis (in vitro). Promotes activation of caspases and apoptosis.
Cellular Location Membrane; Single-pass type II membrane protein
Tissue Location Specifically expressed in endothelial cells. Detected in monocytes, placenta, lung, liver, kidney, skeletal muscle, pancreas, spleen, prostate, small intestine and colon
Research Areas
Citations (0)

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The protein encoded by this gene is a cytokine thatbelongs to the tumor necrosis factor (TNF) ligand family. Thisprotein is abundantly expressed in endothelial cells, but is notexpressed in either B or T cells. The expression of this protein isinducible by TNF and IL-1 alpha. This cytokine is a ligand forreceptor TNFRSF25 and decoy receptor TNFRSF21/DR6. It can activateNF-kappaB and MAP kinases, and acts as an autocrine factor toinduce apoptosis in endothelial cells. This cytokine is also foundto inhibit endothelial cell proliferation, and thus may function asan angiogenesis inhibitor. An additional isoform encoded by analternatively spliced transcript variant has been reported but thesequence of this transcript has not been determined. [provided byRefSeq].


Amre, D.K., et al. Hum. Genet. 128(2):131-135(2010)Heidemann, S.C., et al. J. Clin. Immunol. 30(4):531-538(2010)McLaren, J.E., et al. J. Immunol. 184(10):5827-5834(2010)Davila, S., et al. Genes Immun. 11(3):232-238(2010)Nakagome, S., et al. Ann. Hum. Genet. 74(2):126-136(2010)

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$ 80.00
Cat# BP11879c
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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