|Other Names||V-set and immunoglobulin domain-containing protein 1, Cell surface A33 antigen, Glycoprotein A34, VSIG1, GPA34|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Cellular Location||Membrane; Single-pass type I membrane protein|
|Tissue Location||Detected only in stomach mucosa and testis, and to a much lesser level in pancreas (at protein level) Detected in gastric cancers (31%), esophageal carcinomas (50%) and ovarian cancers (23%).|
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Provided below are standard protocols that you may find useful for product applications.
This gene encodes a member of the junctional adhesionmolecule (JAM) family. The encoded protein contains multipleglycosylation sites at the N-terminal region, and multiplephosphorylation sites and glutamic acid/proline (EP) repeats at theC-terminal region. The gene is expressed in normal stomach andtestis, as well as in gastric, esophageal and ovarian cancers.Alternatively spliced transcript variants encoding differentisoforms have been found for this gene.
Scanlan, M.J., et al. Cancer Immun. 6, 2 (2006) :
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