|Other Names||Rap1 GTPase-GDP dissociation stimulator 1, Exchange factor smgGDS, SMG GDS protein, SMG P21 stimulatory GDP/GTP exchange protein, RAP1GDS1|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Stimulates GDP/GTP exchange reaction of a group of small GTP-binding proteins (G proteins) including Rap1a/Rap1b, RhoA, RhoB and KRas, by stimulating the dissociation of GDP from and the subsequent binding of GTP to each small G protein.|
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Provided below are standard protocols that you may find useful for product applications.
The smg GDP dissociation stimulator (smgGDS) protein is astimulatory GDP/GTP exchange protein with GTPase activity (Riess etal., 1993 [PubMed 8262526]).
Schonherr, C., et al. Oncogene 29(19):2817-2830(2010)Branham, M.T., et al. J. Biol. Chem. 284(37):24825-24839(2009)Zemunik, T., et al. Croat. Med. J. 50(1):23-33(2009)Tew, G.W., et al. J. Biol. Chem. 283(2):963-976(2008)Tiwari, S., et al. Blood 103(7):2661-2667(2004)
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