|Other Names||Smoothelin, SMTN, SMSMO|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Structural protein of the cytoskeleton.|
|Cellular Location||Cytoplasm, cytoskeleton. Note=Exhibits a filamentous organization|
|Tissue Location||Smooth muscle; contractile or vascular (for the long form)|
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This gene encodes a structural protein that is foundexclusively in contractile smooth muscle cells. It associates withstress fibers and constitutes part of the cytoskeleton. This geneis localized to chromosome 22q12.3, distal to the TUPLE1 locus andoutside the DiGeorge syndrome deletion. Alternative splicing ofthis gene results in three transcript variants. [provided byRefSeq].
Bovio, I.M., et al. Histopathology 56(7):951-956(2010)Miyamoto, H., et al. Am. J. Surg. Pathol. 34(3):418-422(2010)Coco, D.P., et al. Am. J. Surg. Pathol. 33(12):1795-1801(2009)Council, L., et al. Mod. Pathol. 22(5):639-650(2009)Beausoleil, S.A., et al. Proc. Natl. Acad. Sci. U.S.A. 101(33):12130-12135(2004)
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