Register or Login
All
  • All
  • Uniprot Id
  • Catalog #
  • Peptide Sequence
>   home   >   Products   >   Peptides   >   Blocking Peptides   >   TFAP4 Antibody (Center) Blocking peptide   

TFAP4 Antibody (Center) Blocking peptide

Synthetic peptide

     
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Primary Accession Q01664
Clone Names 81110051
Peptide ID 81110051
Additional Information
Other Names Transcription factor AP-4, Activating enhancer-binding protein 4, Class C basic helix-loop-helix protein 41, bHLHc41, TFAP4, BHLHC41
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name TFAP4
Synonyms BHLHC41
Function Transcription factor that activates both viral and cellular genes by binding to the symmetrical DNA sequence 5'- CAGCTG-3'.
Cellular Location Nucleus. EMBL; S73885; AAB32235.1; -; mRNA EMBL; AC004653; AAC17116.1; -; Genomic_DNA EMBL; BC010576; AAH10576.1; -; mRNA EMBL; X57435; CAA40683.1; -; mRNA CCDS; CCDS10510.1; - PIR; I56893; I56893 RefSeq; NP_003214.1; NM_003223.2 UniGene; Hs.513305; - ProteinModelPortal; Q01664; - SMR; Q01664; - BioGrid; 112881; 115 DIP; DIP-53627N; - IntAct; Q01664; 25 MINT; Q01664; - STRING; 9606.ENSP00000204517; - iPTMnet; Q01664; - PhosphoSitePlus; Q01664; - BioMuta; TFAP4; - DMDM; 1729833; - EPD; Q01664; - MaxQB; Q01664; - PaxDb; Q01664; - PeptideAtlas; Q01664; - PRIDE; Q01664; - ProteomicsDB; 57980; - DNASU; 7023; - Ensembl; ENST00000204517; ENSP00000204517; ENSG00000090447 GeneID; 7023; - KEGG; hsa:7023; - UCSC; uc010uxg.3; human CTD; 7023; - DisGeNET; 7023; - EuPathDB; HostDB:ENSG00000090447.11; - GeneCards; TFAP4; - HGNC; HGNC:11745; TFAP4 HPA; HPA001912; - MIM; 600743; gene neXtProt; NX_Q01664; - OpenTargets; ENSG00000090447; - PharmGKB; PA36462; - eggNOG; KOG0561; Eukaryota eggNOG; ENOG4111JPE; LUCA GeneTree; ENSGT00390000015189; - HOGENOM; HOG000294087; - HOVERGEN; HBG061473; - InParanoid; Q01664; - KO; K09108; - OMA; HHVNVVT; - OrthoDB; EOG091G194I; - PhylomeDB; Q01664; - TreeFam; TF316489; - SIGNOR; Q01664; - GeneWiki; TFAP4; - GenomeRNAi; 7023; - PRO; PR:Q01664; - Proteomes; UP000005640; Chromosome 16 Bgee; ENSG00000090447; - CleanEx; HS_TFAP4; - ExpressionAtlas; Q01664; baseline and differential Genevisible; Q01664; HS GO; GO:0005739; C:mitochondrion; IDA:HPA GO; GO:0005634; C:nucleus; IDA:UniProtKB GO; GO:0017053; C:transcriptional repressor complex; ISS:UniProtKB GO; GO:0003677; F:DNA binding; IDA:UniProtKB GO; GO:0070888; F:E-box binding; IDA:UniProtKB GO; GO:0042826; F:histone deacetylase binding; IPI:UniProtKB GO; GO:0042803; F:protein homodimerization activity; IPI:UniProtKB GO; GO:0000981; F:RNA polymerase II transcription factor activity, sequence-specific DNA binding; ISA:NTNU_SB GO; GO:0043565; F:sequence-specific DNA binding; IDA:UniProtKB GO; GO:0003705; F:transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding; IDA:UniProtKB GO; GO:0044212; F:transcription regulatory region DNA binding; IDA:UniProtKB GO; GO:0001077; F:transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding; IEA:Ensembl GO; GO:0071549; P:cellular response to dexamethasone stimulus; IEA:Ensembl GO; GO:0006978; P:DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator; IDA:UniProtKB GO; GO:0043922; P:negative regulation by host of viral transcription; IDA:UniProtKB GO; GO:0071157; P:negative regulation of cell cycle arrest; IMP:UniProtKB GO; GO:0008285; P:negative regulation of cell proliferation; IMP:UniProtKB GO; GO:0045736; P:negative regulation of cyclin-dependent protein serine/threonine kinase activity; IDA:UniProtKB GO; GO:0043392; P:negative regulation of DNA binding; IDA:UniProtKB GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:UniProtKB GO; GO:0043923; P:positive regulation by host of viral transcription; IDA:UniProtKB GO; GO:0043065; P:positive regulation of apoptotic process; IDA:UniProtKB GO; GO:2001269; P:positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway; IEA:Ensembl GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IMP:UniProtKB GO; GO:0065003; P:protein-containing complex assembly; IDA:UniProtKB GO; GO:1901990; P:regulation of mitotic cell cycle phase transition; IDA:UniProtKB CDD; cd00083; HLH; 1 Gene3D; 4.10.280.10; -; 1 InterPro; IPR011598; bHLH_dom InterPro; IPR036638; HLH_DNA-bd_sf Pfam; PF00010; HLH; 1 SMART; SM00353; HLH; 1 SUPFAM; SSF47459; SSF47459; 1 PROSITE; PS50888; BHLH; 1 1: Evidence at protein level; Activator; Complete proteome; Direct protein sequencing; DNA-binding; Isopeptide bond; Nucleus; Phosphoprotein; Polymorphism; Reference proteome; Repeat; Transcription; Transcription regulation; Ubl conjugation CHAIN 1 338 Transcription factor AP-4 /FTId=PRO_0000127458 DOMAIN 48 99 bHLH. {ECO:0000255|PROSITE- ProRule:PRU00981} REGION 100 120 Leucine-zipper 1 REGION 151 179 Leucine-zipper 2 COMPBIAS 193 222 Gln-rich COMPBIAS 225 244 Pro-rich MOD_RES 123 123 Phosphoserine MOD_RES 124 124 Phosphoserine MOD_RES 139 139 Phosphoserine CROSSLNK 147 147 Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) CROSSLNK 187 187 Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) CROSSLNK 189 189 Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) CROSSLNK 285 285 Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) VARIANT 218 218 Q -> H (in dbSNP:rs251732) /FTId=VAR_059346 SEQUENCE 338 AA; 38726 MW; 540C008658596B83 CRC64; MEYFMVPTQK VPSLQHFRKT EKEVIGGLCS LANIPLTPET QRDQERRIRR EIANSNERRR MQSINAGFQS LKTLIPHTDG EKLSKAAILQ QTAEYIFSLE QEKTRLLQQN TQLKRFIQEL SGSSPKRRRA EDKDEGIGSP DIWEDEKAED LRREMIELRQ QLDKERSVRM MLEEQVRSLE AHMYPEKLKV IAQQVQLQQQ QEQVRLLHQE KLEREQQQLR TQLLPPPAPT HHPTVIVPAP PPPPSHHINV VTMGPSSVIN SVSTSRQNLD TIVQAIQHIE GTQEKQELEE EQRRAVIVKP VRSCPEAPTS DTASDSEASD SDAMDQSREE PSGDGELP
Research Areas
Citations (0)

Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.

Submit your citation using an Abgent antibody to
info@abgent.com, and receive a free "I Love Antibodies" mug.

Background

Transcription factors of the basic helix-loop-helix-zipper(bHLH-ZIP) family contain a basic domain, which is used for DNAbinding, and HLH and ZIP domains, which are used foroligomerization. Transcription factor AP4 activates both viral andcellular genes by binding to the symmetrical DNA sequence CAGCTG(Mermod et al., 1988 [PubMed 2833704]; Hu et al., 1990 [PubMed2123466]).

References

Ku, W.C., et al. Mol. Cell Proteomics 8(9):2034-2050(2009)Cao, J., et al. Int. J. Surg. Pathol. 17(1):16-21(2009)Jung, P., et al. Proc. Natl. Acad. Sci. U.S.A. 105(39):15046-15051(2008)Pons, J., et al. Biochemistry 47(1):14-29(2008)Sugiyama, N., et al. Mol. Cell Proteomics 6(6):1103-1109(2007)

FeedBack
Abgent welcomes feedback from its customers.

If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.

If you have any additional inquiries please email technical services at tech@abgent.com.

$ 80.00
Cat# BP11969c
Size:
Quantity:
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
Request Quote Here

Ordering Information

United States
AlbaniaAustraliaAustriaBelgiumBosnia & HerzegovinaBrazilBulgariaCanadaCentral AmericaChinaCroatiaCyprusCzech RepublicDenmarkEstoniaFinlandFranceGermanyGreeceHong KongHungaryIcelandIndiaIndonesiaIrelandIsraelItalyJapanLatviaLithuaniaLuxembourgMacedoniaMalaysiaMaltaNetherlandsNew ZealandNorwayPakistanPolandPortugalRomaniaSerbiaSingaporeSlovakiaSloveniaSouth AfricaSouth KoreaSpainSwedenSwitzerlandTaiwanTurkeyUnited KingdomUnited StatesVietnamWorldwideOthers
Abgent, Inc.
(888) 735-7227 / (858) 622-0099
(858) 622-0609
USA Headquarters
(888) 735-7227 / (858) 622-0099 or (858) 875-1900

Shipping Information

Domestic orders (in stock items)
Shipped out the same day. Orders placed after 1 PM (PST) will ship out the next business day.
International orders
Contact your local distributors
“Crown Flash”  50 % off on 2,500+ Crown Antibodies. PromoCode:<span class=text-red> FLASH50
Terms & Conditions