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>   home   >   Products   >   Peptides   >   Blocking Peptides   >   EIF5AL1 Antibody (C-term) Blocking peptide   

EIF5AL1 Antibody (C-term) Blocking peptide

Synthetic peptide

     
  • SPECIFICATION
  • CITATIONS
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Product Information
Primary Accession Q6IS14
Clone Names 100408145
Peptide ID 100408145
Additional Information
Gene ID 143244
Other Names Eukaryotic translation initiation factor 5A-1-like, eIF-5A-1-like, eIF-5A1-like, Eukaryotic initiation factor 5A isoform 1-like, EIF5AL1
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name EIF5AL1
Function mRNA-binding protein involved in translation elongation. Has an important function at the level of mRNA turnover, probably acting downstream of decapping. Involved in actin dynamics and cell cycle progression, mRNA decay and probably in a pathway involved in stress response and maintenance of cell wall integrity. Functions as a regulator of apoptosis. Mediates effects of polyamines on neuronal process extension and survival. May play an important role in brain development and function, and in skeletal muscle stem cell differentiation (By similarity).
Cellular Location Cytoplasm. Nucleus. Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side. Nucleus, nuclear pore complex Note=Hypusine modification promotes the nuclear export and cytoplasmic localization and there was a dynamic shift in the localization from predominantly cytoplasmic to primarily nuclear under apoptotic inducing conditions.
Research Areas
Citations (0)

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Background

EIF5AL1is a mRNA-binding protein involved in translation elongation. Has an important function at the level of mRNA turnover, probably acting downstream of decapping. Involved in actin dynamics and cell cycle progression, mRNA decay and probably in a pathway involved in stress response and maintenance of cell wall integrity. Functions as a regulator of apoptosis. Mediates effects of polyamines on neuronal process extension and survival. May play an important role in brain development and function, and in skeletal muscle stem cell differentiation (By similarity).

References

Kim, S.C., et al. Mol. Cell 23(4):607-618(2006)Clement, P.M., et al. FEBS J. 273(6):1102-1114(2006)Facchiano, A.M., et al. Protein Eng. 14(11):881-890(2001)Lipowsky, G., et al. EMBO J. 19(16):4362-4371(2000)Koettnitz, K., et al. Gene 159(2):283-284(1995)

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$ 80.00
Cat# BP11986b
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