ELMD2 Antibody (C-term) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q8IZ81 |
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Clone Names | 91201184 |
Gene ID | 255520 |
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Other Names | ELMO domain-containing protein 2, ELMOD2 |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | ELMOD2 |
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Function | Acts as a GTPase-activating protein (GAP) toward guanine nucleotide exchange factors like ARL2, ARL3, ARF1 and ARF6, but not for GTPases outside the Arf family. Regulates IFN-related antiviral responses. |
Tissue Location | Alveolar cells (morphologically type II cells) and alveolar macrophages (at protein level). Expressed in brain, colon, heart, kidney, liver, lung, muscle, placenta, small intestine, spleen, stomach and testis. In lung it is expressed in alveolar macrophages and alveolar walls. |
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes one of six engulfment and motility(ELMO) domain-containing proteins. This gene is thought to play arole in antiviral responses. Mutations in this gene may be involvedin the cause of familial idiopathic pulmonary fibrosis. [providedby RefSeq].
References
Pulkkinen, V., et al. FASEB J. 24(4):1167-1177(2010)Bowzard, J.B., et al. J. Biol. Chem. 282(24):17568-17580(2007)Hodgson, U., et al. Am. J. Hum. Genet. 79(1):149-154(2006)
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