|Other Names||Olfactory receptor 2J3, Hs6M1-3, Olfactory receptor OR6-16, OR6-6, Olfactory receptor 6-6, OR2J3|
|Target/Specificity||The synthetic peptide sequence is selected from aa 262-275 of HUMAN OR2J3|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Odorant receptor involved in the detection of the flavor compound cis-3-hexen-1-ol (C3HEX), a compound typically described as 'green grassy' or the smell of 'cut grass'.|
|Cellular Location||Cell membrane; Multi-pass membrane protein.|
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Provided below are standard protocols that you may find useful for product applications.
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.
Barcellos, L.F., et al. PLoS Genet. 5 (10), E1000696 (2009) : Menashe, I., et al. BMC Bioinformatics 7, 393 (2006) : Malnic, B., et al. Proc. Natl. Acad. Sci. U.S.A. 101(8):2584-2589(2004) Fuchs, T., et al. Genomics 80(3):295-302(2002) Glusman, G., et al. Genome Res. 11(5):685-702(2001)
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