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PCDH1 Antibody (N-term) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q08174 |
|---|---|
| Clone Names | 101008055 |
| Gene ID | 5097 |
|---|---|
| Other Names | Protocadherin-1, Cadherin-like protein 1, Protocadherin-42, PC42, PCDH1 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | PCDH1 |
|---|---|
| Function | May be involved in cell-cell interaction processes and in cell adhesion. |
| Cellular Location | Cell junction. Cell membrane; Single-pass type I membrane protein. Note=Found at cell- cell boundaries and probably at cell-matrix boundaries |
| Tissue Location | Highly expressed in the brain and neuro-glial cells |
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene belongs to the protocadherin subfamily withinthe cadherin superfamily. The encoded protein is a membrane proteinfound at cell-cell boundaries. It is involved in neural celladhesion, suggesting a possible role in neuronal development. Theprotein includes an extracelllular region, containing 7cadherin-like domains, a transmembrane region and a C-terminalcytoplasmic region. Cells expressing the protein showed cellaggregation activity. Alternative splicing occurs in this gene.
References
Koppelman, G.H., et al. Am. J. Respir. Crit. Care Med. 180(10):929-935(2009)Rush, J., et al. Nat. Biotechnol. 23(1):94-101(2005)Ballif, B.A., et al. Mol. Cell Proteomics 3(11):1093-1101(2004)Ballif, B.A., et al. Mol. Cell Proteomics 3(11):1093-1101(2004)Colland, F., et al. Genome Res. 14(7):1324-1332(2004)
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