Register or Login
  • All
  • Uniprot Id
  • Catalog #
  • Peptide Sequence
>   home   >   Products   >   Peptides   >   Blocking Peptides   >   CASP12 Antibody (Center) Blocking peptide   

CASP12 Antibody (Center) Blocking peptide

Synthetic peptide

Product Information
Primary Accession Q6UXS9
Clone Names 101008110
Peptide ID 101008110
Additional Information
Gene ID 100506742
Other Names Inactive caspase-12, CASP-12, CASP12
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name CASP12
Function Has no protease activity. May reduce cytokine release in response to bacterial lipopolysaccharide during infections. Reduces activation of NF-kappa-B in response to TNF.
Tissue Location Detected in heart, kidney, liver, lung, pancreas, small intestine, spleen, stomach, thymus and testis
Research Areas
Citations (0)

Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.

Submit your citation using an Abgent antibody to, and receive a free "I Love Antibodies" mug.


Caspases are cysteine proteases that cleave C-terminalaspartic acid residues on their substrate molecules. This gene ismost highly related to members of the ICE subfamily of caspasesthat process inflammatory cytokines. In rodents, the homolog ofthis gene mediates apoptosis in response to endoplasmic reticulumstress. However, in humans this gene contains a polymorphism forthe presence or absence of a premature stop codon. The majority ofhuman individuals have the premature stop codon and produce atruncated non-functional protein. The read-through codon occursprimarily in individuals of African descent and carriers haveendotoxin hypo-responsiveness and an increased susceptibility tosevere sepsis. Several alternatively spliced transcript variantshave been noted for this gene.


Lee, H.J., et al. Arch. Biochem. Biophys. 502(1):68-73(2010)Plantinga, T.S., et al. J. Acquir. Immune Defic. Syndr. 55(1):87-94(2010)McCall, M.B., et al. Eur. Cytokine Netw. 21(2):77-83(2010)Kachapati, K., et al. Hum. Mutat. 27 (9), 975 (2006) :Xue, Y., et al. Am. J. Hum. Genet. 78(4):659-670(2006)

Abgent welcomes feedback from its customers.

If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.

If you have any additional inquiries please email technical services at

$ 80.00
Cat# BP12027c
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
Request Quote Here

Ordering Information

United States
AlbaniaAustraliaAustriaBelgiumBosnia & HerzegovinaBrazilBulgariaCanadaChinaCroatiaCyprusCzech RepublicDenmarkEstoniaFinlandFranceGermanyGreeceHong KongHungaryIcelandIndiaIndonesiaIrelandIsraelItalyJapanKoreaLatviaLithuaniaLuxembourgMacedoniaMalaysiaMaltaNetherlandsNew ZealandNorwayPakistanPolandPortugalRomaniaSerbiaSingaporeSlovakiaSloveniaSouth AfricaSpainSwedenSwitzerlandTaiwanTurkeyUnited KingdomUnited StatesVietnamOthers
Abgent, Inc.
(888) 735-7227 / (858) 622-0099
(858) 622-0609

Shipping Information

Domestic orders (in stock items)
Shipped out the same day. Orders placed after 1 PM (PST) will ship out the next business day.
International orders
Contact your local distributors
Santa Cruz Alternative
Terms & Conditions