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DOK3 Antibody (C-term) Blocking peptide

Synthetic peptide

     
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Product Information
Primary Accession Q7L591
Clone Names 101008016
Peptide ID 101008016
Additional Information
Gene ID 79930
Other Names Docking protein 3, Downstream of tyrosine kinase 3, DOK3
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name DOK3
Function DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK3 is a negative regulator of JNK signaling in B-cells through interaction with INPP5D/SHIP1. May modulate ABL1 function (By similarity).
Cellular Location Cytoplasm. Cell membrane; Peripheral membrane protein; Cytoplasmic side
Tissue Location Expressed in spleen.
Research Areas
Citations (0)

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Background

DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK3 is a negative regulator of JNK signaling in B-cells through interaction with INPP5D/SHIP1. May modulate Abl function (By similarity).

References

Berger, A.H., et al. Nat. Genet. 42(3):216-223(2010)Senis, Y.A., et al. J. Thromb. Haemost. 7(10):1718-1726(2009)Honma, M., et al. Genes Cells 11(2):143-151(2006)Robson, J.D., et al. Mol. Cell. Biol. 24(6):2332-2343(2004)Favre, C., et al. Genes Immun. 4(1):40-45(2003)

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$ 80.00
Cat# BP12040b
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